pathology Disease pathology is caused by the body’s immune response to antigens coating the eggs circulating the body. The disease covers a range of clinical symptoms according to species. Two main forms of human schistosomiasis are recognised, both with differentially associated pathology: urogenital schistosomiasis, resulting from infection by S. haematobium, affects over 112 million people in sub-Saharan Africa and is associated with haematuria, bladder damage, hydronephrosis with a risk of progression to severe disease such as kidney failure and bladder cancer. Intestinal schistosomiasis in sub-Saharan Africa is mainly caused by infection with S. mansoni, estimated to be the cause of bloody diarrhoea in 4.4 million people, and hepato-splenomegaly, a severe clinical manifestation of the disease is estimated to affect 8.5 million people. In Aisa, S. japonicum is the main causal agent of intestinal schistosomiasis. |
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Taxonomic name:
Schistosoma (Parasite taxonomy), Planorbidae (Taxonomy of Hosts), Pomatiopsidae (Taxonomy of Hosts), Bulinus (Taxonomy of Hosts), Biomphalaria (Taxonomy of Hosts), Radix (Taxonomy of Hosts), Oncomelania (Taxonomy of Hosts), Neotricula (Taxonomy of Hosts), Schistosomatidae (Parasite taxonomy), Schistosoma haematobium (Parasite taxonomy)